Estrogen Metabolism and Cancer Risk

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چکیده

The human embryo develops into a woman as a result of estrogen. It helps maintain our breasts, genitalia, vagina, cervix, and parts of our urinary tract. These tissues are estrogen sensitive. Estrogen, though beneficial in many ways to women, has also been linked to cancer of the breast, uterine lining, and cervix. Excessive amounts of estrogen and prolonged exposure to it, can increase our risk for cancer. The same is true for endogenous (produced by ovaries, fat, skin, etc.) and exogenous (estrogen containing contraceptives, hormone replacement, herbicides, pesticides, etc.) estrogens. We may be particularly sensitive to, or may not metabolize estrogen in a healthy manner due to our genetic makeup.

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تاریخ انتشار 2012